Mean Platelet Volume

The mean platelet volume or MPV result

is produced by a machine called an automated analyser, and is a calculation of the average size of your platelets, (rather like MCV is a calculation of the average size of individual red blood cells).

Normal Range

7.5-11.5 fl

What abnormal results mean.

If the MPV is decreased

it means the platelets are smaller than normal. They are now known as Microthrombocytes.

This may indicate the following disorders:-

1. Aplastic Anemia -

A rare acquired disorder in which your bone marrow stops producing new blood cells.

2. Wiskott-Aldrich Syndrome -

An inherited immune deficiency disease, one of whose main symptoms is a tendency to bleed due to a low platelet count.

3. Thrombocytopenia-absent radii (TAR Syndrome) -

A rare disorder in which there are low platelets and absence of the radius bones in the arms.

4. Storage Pool Disease -

A mild bleeding disorder that causes bruising.

If the MPV is increased

it means the platelets are larger than normal. They are now known as Microthrombocytes.

This may indicate the following disorders:-

1. Idiopathic Thrombocytopenic Purpura -

A bleeding disorder in which the blood does not clot as it should.

2. Bernard-Soulier Disease -

A congenital disorder where the platelets lack receptors to adhere to the walls of the blood vessels.

3. May-Hegglin Anomaly -

A rare, inherited disorder characterised by abnormally large platelets.

4 Greater risk of heart attacks and stroke

Due to increased numbers of large, hyperaggregable platelets

5. Increased platelet activation -

As younger platelets tend to be larger than older ones an increase indicates that increased numbers are being produced. This gives the doctor information about the platelet production capabilities of the bone marrow.



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